Retrospective study of laparoscopic splenic artery ligation combined with pericardial devascularization for portal hypertension in cirrhosis
[Objective]To investigate the therapeutic effect of laparoscopic splenic artery ligation(SAL)combined with pericardial devascularization(EED)in the treatment of liver cirrhosis portal hypertension(PHT).[Methods]Clinical data of 126 cirrhotic PHT patients admitted to Anyang Third People's Hospital and Anyang Fifth People's Hospital from July 2020 to May 2023 were retrospectivly studied,and the patients were divided into observation group(69 cases,laparoscopic SAL combined with EED)and control group[57 cases,laparoscopic splenectomy(LS)combined with EED].Perioperative indicators were compared between the two groups:preoperative and postoperative 14-day blood routine indexes[platelet count(PLT),white blood cell count(WBC),red blood cell count(RBC)],liver function index[transglutamase(ALT),glutamicum transaminase(AST),y-glutamyl transpeptidase(GGT)],coagulation index[activated partial thromboplastin time(APTT),fibrinogen(FIB),prothrombin time(PT)],and the occurrence of postoperative complications was observed.[Results]All perioperative indicators of the observation group were lower than those of the control group(P＜0.05).Fourteen days after surgery,PLT and WBC levels of the observation group were lower than those of the control group(P＜0.05),and there was no statistical difference in RBC level between the two groups(P＞0.05).In the observation group,ALT,AST,GGT,APTT,and PT were lower,and FIB was higher than those in the control group(P＜0.05).The overall incidence of postoperative complications of the observation group was lower than that of the control group(P＜0.05).[Conclusion]Laparoscopic SAL combined with EED can improve the surgical effect of PHT,improve hypersplenism,improve liver function and coagulation function,and reduce the occurrence of complications.
laparoscopic splenic artery ligationpericardial devascularizationportal hypertension in cirrhosis
万方数据
维普
