Research progress of extracellular matrix hydrogel materials for spinal cord injury repair
Spinal cord injury(SCI)is a severe traumatic disease of the central nervous system that can lead to loss of motor and sensory function.Due to its complex pathological mechanism,the treatment of this disease still faces great challenges.Hydrogels have good biocompatibility and biodegradability and can mimic the extracellular matrix in the spinal cord microenvironment.In recent years,hydrogel has been recognized as a promising material for spinal cord injury repair,and continuous research has confirmed that hydrogel therapy can effectively eliminate inflammation and promote spinal cord repair and regeneration,thereby improving spinal cord injury.This article summarizes the recent research progress of spinal extracellular matrix hydrogels to further elucidate their specific mechanism in spinal cord injury repair and provide a new method for the treatment of spinal cord injury.