Effect of Xingnaojing injection combined with argatroban on neurological function in patients with cerebral infarction
[Objective]To investigate the effect of Xingnaojing injection combined with argatroban on the neurological function of patients with cerebral infarction during the treatment of cerebral infarction.[Methods]A random number table method was used to select patients diagnosed with cerebral infarction from January 2021 to January 2023 in Luoyang Dongfang People's Hospital,64 of them were screened as subjects and divided into two groups.There were 32 patients in each group.Conventional indexes were performed first in both groups,and routine lipids lowering,blood pressure and blood glucose regulation,blood circulation and blood stasis removal and oxygen inhalation were performed.The control group was treated with argatroban on this basis,and the study group was treated with Xingnaojing injection on the basis of the control group.The clinical therapeutic effects of the two groups were compared,and the score of stroke scale(NIHSS)and Barthel index were recorded and analyzed,as well as the adverse reactions in the later stage of treatment.[Results]After treatment,the total clinical effective rate was 96.87％in the study group and 78.12％in the control group,which was higher in the study group and lower in the control group(P＜0.05).After treatment,the NIHSS score of the two groups showed a downward trend,and the study group was lower than the control group,and the Barthel index score showed an upward trend,and the study group was higher than the control group(P＜0.05).Adverse reactions can occur in patients after treatment,the incidence was 18.75％in the control group and 3.13％in the study group,which was lower in the study group(P＜0.05).[Conclusion]Xingnaojing injection combined with argatroban has good clinical effect in the treatment of cerebral infarction,effectively promoting the recovery of nerve function,improving the daily activity ability of patients,with less adverse reactions and high safety.
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