Occurrence and influencing factors of low anterior resection syndrome after peritoneoscopically assisted transanal total mesangectomy
[Objective]To investigate the occurrence and influencing factors of low anterior resection syndrome after peritoneoscopically assisted transanal total mesorectal excision(TaTME),and to provide evidence for improving defecation function in rectal cancer patients treated with TaTME in the future.[Methods]Sixty-two patients treated with laparoscopic TaTME for middle and low rectal cancer admitted to the Gastrointestinal Surgery Department of Huizhou Central People's Hospital from January 2019 to January 2023 were selected and divided into low anterior resection syndrome(LARS)group and FLARS group according to LARS scale score 3 months and 6 months after surgery.The influencing factors of LARS at 3 and 6 months after operation were analyzed respectively(univariate and multivariate regression analysis).[Results]The incidence of LARS at 3 months after surgery was 66.13％,which was significantly higher than that at 6 months after surgery(41.94％)(P＜0.05).Univariate and multivariate analysis at 3 months after surgery showed that the independent risk factors for LARS were tumor diameter,preoperative rate of radiotherapy and chemotherapy and the distance from the anastomosis to the anal margin.Univariate and multivariate analysis at 6 months after surgery showed that the independent risk factors for LARS were the rate of preoperative chemoradiation and the distance between anastomosis and anal margin.[Conclusion]The incidence of LARS 3 months after laparoscopic-assisted TaTME in the treatment of low and middle rectal cancer patients was significantly higher than that 6 months after surgery,which was closely related to postoperative rehabilitation training and disease recovery.The independent risk factors for LARS after TaTME surgery are synchronous chemoradiation,postoperative distance from the anastomosis to the anal margin(＜2 cm),and tumor diameter(≥5 cm).Attention and intervention should be paid during surgery to reduce the incidence of LARS after surgery and improve the defecation function of patients.
laparoscope-assisted transanal total mesorectal excisionlow anterior resection syndromemiddle and low rectal cancerinfluencing factors
万方数据
维普
