Value of procalcitonin,C-reactive protein,and white blood cell levels in differential diagnosis of acute bacterial infections in children
[Objective]To analyze the value of procalcitonin(PCT),C-reactive protein(CRP),and white blood cell(WBC)levels in the differential diagnosis of acute bacterial infections in children.[Methods]A survey was conducted on 186 children with acute respiratory infections who were hospitalized at Zhengzhou Seventh People's Hospital from March 2022 to June 2023.Fifty-eight children who detected bacteria through sputum culture were classified as Group A,66 children who were found to have common respiratory viruses through serological testing were classified as Group B,and 62 children who were found to have Mycoplasma pneumoniae through serological testing were classified as Group C.Detect the levels of PCT,CRP,and WBC in all study subjects,perform receiver operating characteristic(ROC)curve analysis on acute bacterial infections,and calculate the area under the curve(AUC).[Results]The levels of PCT,CRP,and WBC in Group A were significantly higher than those in Group B and Group C(P＜0.05).ROC curve analysis showed that the area under the curve for PCT,CRP,WBC,and three combined diagnoses were 0.686(0.631-0.742,P＜0.001),0.516(0.408-0.625,P=0.757),0.582(0.515-0.650,P=0.016),and 0.779(0.730-0.827,P＜0.001),respectively.Among 58 cases of bacterial respiratory tract infection,34 cases(58.62％)were Gram positive(G+)bacterial infections,and 24 cases(41.38％)were Gram negative(G-)bacterial infections.There was no significant difference in PCT,CRP,WBC levels,and diagnostic positivity between the main G+and G-bacterial infection groups(P＞0.05).[Conclusion]PCT,CRP,and WBC can be effective indicators for identifying acute bacterial or non-bacterial infections in children,and their levels can prompt clinical doctors to pay attention to the types of pathogens and try to avoid overuse of antibiotics as much as possibletheir.
万方数据
维普
