Effect of aerosol inhalation of budesonide combined with phentolamine on children with infectious pneumonia
[Objective]To explore the effect of aerosol inhalation of budesonide combined with phentolamine in the treatment of children with infectious pneumonia.[Methods]Eighty-two children with infectious pneumonia admitted to Second Affiliated Hospital of Henan University of Science and Technology from July 2019 to September 2022 were selected as the research objects.According to the random number table,they were divided into the test group(41 cases)and the matched group(41 cases).The matched group was treated with atomized budesonide,and the test group was treated with atomized budesonide combined with phentolamine.The clinical effects of the two groups were compared,the levels of inflammatory factors[procalcitonin(PCT),C-reactive protein(CRP),interleukin 6(IL-6)]before and after treatment,as well as the occurrence of adverse reactions.[Results]The clinical efficacy of the test group(39 cases/41 cases,95.12％)was significantly higher than that of the matched group(32 cases/41 cases,78.05％)(P＜0.05).After treatment,the PCT,CRP,and IL-6 levels in the test group and matched group decreased on average,and the PCT,CRP,and IL-6 levels in the test group were lower on average than those in the matched group(P＜0.05).The total incidence of adverse reactions in the test group and matched group was 4.88％(2 cases/41 cases)and 9.76％(4 cases/41 cases),respectively,without a difference that is obviously significant(P＞0.05).[Conclusion]After the treatment of aerosol inhalation of budesonide combined with phentolamine in children with infectious pneumonia,the clinical efficacy of children with infectious pneumonia has significantly improved,and their inflammatory reaction have been improved,with high clinical application value.
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