Influencing factors of oseltamivir phosphate on the prognosis of adult influenza
[Objective]To explore the influencing factors of oseltamivir phosphate on the prognosis of adult influenza,and to provide reference for clinical therapeutic use.[Methods]A total of 100 cases of influenza patients admitted to the Infectious Diseases Department of Zhengzhou Seventh People's Hospital from January 2021 to February 2023 were given oseltamivir phosphate capsule by oral administration to observe the therapeutic effect and prognostic factors of the patients.[Results]After treatment,30 cases were cured,10 cases were effective and 10 cases were ineffective.The total clinical effective rate was 80.00％.Statistically significant indicators with single factor P＜0.05,such as fever,hypersensitive C-reactive protein,severe pneumonia,interleukin-6,aspartic acid transferase,alanine aminotransferase and albumin,were included in Logistic regression analysis,and clinical efficacy was taken as dependent variable(good prognosis=l,poor prognosis=0).The results of clinical analysis showed that severe pneumonia and hypersensitive C-reactive protein were the risk factors affecting the efficacy of oseltamivir(P＜0.05).[Conclusion]Severe pneumonia and hypersensitive C-reactive protein are prognostic factors affecting the clinical efficacy of oseltamivir in the treatment of influenza,so the use of oseltamivir phosphate in clinical treatment should be strictly controlled.
万方数据
维普
