Application value of prenatal Hcy,early vitamin D level and peripheral blood combined detection in the screening of gestational diabetes mellitus
[Objective]To investigate the application value of combined detection of Hcy,early vitamin D and peripheral blood in the screening of gestational diabetes mellitus.[Methods]A total of 82 pregnant women who were examined in Luoyang Maternal and Child Health Hospital from February 2020 to May 2022 were selected as the study objects.A random number table method was used to divide them into two groups according to whether they had gestational diabetes.Pregnant women with gestational diabetes were classified as the study group(41 cases),and those without gestational diabetes were classified as the control group(41 cases).The prenatal Hcy,early vitamin D levels and peripheral blood indicators of the two groups were compared to evaluate the clinical predictive value of combined detection in gestational diabetes patients.[Results]The Hcy index level of the study group was significantly higher than that of the control group,and the vitamin D index was lower than that of the control group(P<0.05).The levels of HbA1c and PLR indexes in the study group were significantly higher than those in the control group(P<0.05).ROC curve was established,and the curve results showed that the area under the curve of single detection of Hcy during pregnancy,early vitamin D level,peripheral blood indicators(HbA1c,PLR)and the combined detection was 0.984 0.921,0.909,0.658,and 0.996,respectively,indicating that the combined detection had a good value in predicting and diagnosing gestational diabetes mellitus.[Conclusion]The combined detection of Hcy,early vitamin D and peripheral blood in pregnancy has good diagnostic value for gestational diabetes mellitus.Detection of sensitive indicators provides objective indicator support for clinical diagnosis of gestational diabetes mellitus,which is of great significance for health care management during pregnancy.