[Objective]To investigate the clinical application of the choroidal fissure approach to the lateral ventricle of the frontal lostomy in the treatment of thalamic glioblastoma.[Methods]The clinical data,surgical methods and postoperative follow-up data of 21 patients with thalamic glioblastoma treated by frontal lostomy lateral ventricle choroidal fissure approach were analyzed retrospectively.[Results]Total resection was achieved in all 17 cases,and subtotal resection in 4 cases.There were postoperative hydrocephalus in 5 cases and intracranial infection in 3 cases.Symptoms disappeared or improved in 18 patients with headache and dizziness before surgery.Patients were followed up for 6 to 40 months,with an average of 24.7 months.Tumor recurrence in 2 patients with subtotal resection,and no recurrence in the remaining patients,and tumor resection again in 1 patient with subtotal resection.Postopcrative new symptoms were improved to different degrees.[Conclusion]The clinical application of transfrontal lostomy lateral ventricle choroidal fissure approach in the treatment of thalamic glioblastoma is satisfactory.
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