Correlation analysis between thromboelastogram parameters and coagulation indexes,platelete count in patients undergoing cardiopulmonary bypass
[Objective]To analyze the correlation between thrombelastogram(TEG)parameters and coagulation indexes,platelet count(PLT)in patients undergoing cardiopulmonary bypass.[Methods]From July 2020 to November 2022,68 patients who underwent cardiopulmonary bypass heart surgery in Nanyang Central Hospital were retrospectively analyzed with TEG,routine blood coagulation test and PLT before and after surgery.The relationship among coagulation response time(R value),clot formation time(K value),clot formation rate(α),maximum amplitude(MA value),blood clotting index(BCI),prothrombin time(PT),activated partial thromboplastin time(APTT),fibrinogen(Fib),thrombin time(TT)and PLT were analyzed.[Results]There was no significant difference in R value,K value,α angle and BCI in the thrombus elastogram of 68 patients before and after operation(P＞0.05).The postoperative MA value was significantly lower than that before operation,and the difference was statistically significant(P＜0.05).PLT decreased significantly after operation,while PT,APTT,Fib and TT levels increased significantly after operation,with statistical significance(P＜0.05).Pearson correlation analysis showed that TEG parameters was significantly correlated with coagulation index and platelet count,in which R value was positively correlated with PT,K value,K value with PT,APTT,α angle with MA,MA with PLT;R value and α angle,BCI,K value and α angle,BCI,MA,α angle and PT,APTT,MA and APTT were negatively correlated(P＜0.05).[Conclusion]There is a large correlation between thrombelastogram parameters,coagulation index and platelet count in patients undergoing cardiac surgery under cardiopulmonary bypass.The combination of thrombelastogram and coagulation test can better understand the perioperative coagulation function of patients and ensure the safety of patients.
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