Risk factors and predictive efficacy of periprosthesis infection after primary hip arthroplasty
[Objective]To investigate the risk factors and further analyze the predictive efficacy aims to provide more reference information for clinical prevention and treatment.[Methods]Eighty-six patients who underwent initial artificial hip arthroplasty in Dengzhou Central Hospital from January 2020 to January 2023 were retrospectively included.They were divided into infected group(12 cases)and uninfected group(74 cases)according to whether periprosthesis infection occurred during 1-year follow-up.The independent risk factors for periprosthesis infection after primary hip arthroplasty were evaluated by single factor and multifactor methods to further evaluate the clinical efficacy of these risk factors in predicting the risk of periprosthesis infection after primary hip arthroplasty.[Results]The results of univariate analysis showed that body mass index,the proportion of diabetes mellitus,the cause of hip replacement,the type of prosthesis,the time of operation and the amount of blood loss during hip replacement may be related to periprosthesis infection after primary hip replacement(P<0.05).Multivariate analysis of logistic regression model showed that the operative time of more than 120 minutes,diabetes mellitus and hip tumor were independent risk factors for periprosthesis infection after primary hip replacement(P<0.05).Reciever operating characteristic(ROC)curve analysis showed that operative time,diabetes combined with hip tumor could all be used to predict the risk of periprosthesis infection after primary hip replacement,and the area under the curve(AUC)of combined prediction was 0.89(95%CI:0.84 to 0.96),the sensitivity and specificity were 88.56%and 86.29%,respectively,and the prediction efficiency was significantly better than that of single risk factor(P<0.05).[Conclusion]Periprosthesis infection after primary hip arthroplasty may be related to operation time,diabetes mellitus and hip arthroplasty.The combined use of the above three indicators to predict the risk of postoperative periprosthesis infection showed satisfactory clinical efficacy.
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