摘要
目的 观察针刺治疗儿童单纯性肥胖(胃热湿阻型)的临床疗效.方法 通过网络随机方法将120例单纯性肥胖儿童(胃热湿阻型)分为对照组和观察组各60例.对照组采取饮食+运动管理方案,观察组在此基础上加用针刺疗法.治疗12周后对比两组临床疗效与干预前后肥胖指标[体质量、体脂率与体质量指数(BMI)]、中医证候积分、瘦素与血清胰岛素情况.结果 (1)观察组治疗总有效率为86.7％(52/60),明显高于对照组40.0％(24/60),差异有统计学意义(P＜0.05).(2)两组治疗方案对单纯性肥胖患儿的体质量、BMI、体脂率、中医证候积分、胰岛素和瘦素水平改善的差异有统计学意义(P＜0.05),说明针刺联合饮食管理加运动方案优于单纯饮食管理加运动方案.结论 针刺疗法是治疗儿童单纯性肥胖的有效手段,可显著改善患儿体质量、BMI、体脂率及中医证候,其机制可能与改善糖代谢、瘦素抵抗,抑制食欲等有关.
Abstract
Objective To observe the clinical efficacy of acupuncture treatment for children with simple obesity characterized by stomach heat and dampness blockage.Methods A total of 120 children diagnosed with simple obesity(stomach-heat and dampness-blockage type)were randomly assigned into two groups by an online random method,each consisting of 60 participants:a control group receiving dietary and exercise management,and an observation group that additionally received acupuncture therapy.After a treatment period of 12 weeks,we compared the clinical outcomes as well as changes in obesity indexes(body weight,body fat percentage,and body mass index),traditional Chinese medicine syndrome scores,leptin levels,and serum insulin between the two groups.Results(1)The overall effective rate of the observation group was 86.7％(52/60),significantly higher that that of the control group(40.0％,24/60),the difference being of statistical significance(P＜0.05).(2)Both treatment regimens exhibited statistically significant differences in their effects on body weight,BMI,body fat percentage,TCM syndrome scores,insulin and leptin levels among children with simple obesity(P＜0.05),which showed that combining acupuncture with dietary management plus exercise was superior to solely diet management plus exercise.Conclusion Acupuncture therapy is an effective intervention for childhood simple obesity;it markedly improves body weight,BMI,body fat percentage and TCM syndrome scores,whose mechanism may be related to improving glucose metabolism and leptin resistance,and inhibiting appetite.
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