Advances of Targeted Drug Resistance Mechanism in the Treatment of Malignant Melanoma Chronic Disease
Malignant melanoma(MM)is a high-grade malignant tumor formed by the malignant transformation of melanocytes,and its fatality and incidence rate are increasing year by year.Although targeted therapy and the use of immune checkpoint inhibitors have improved the survival rate of patients with advanced MM in recent years,there are still problems such as tolerance and ineffective treatment.As a classic drug for the treatment of MM patients,the mechanism of resistance to MM and the subsequent treatment regimen need to be solved urgently.This article will review the drug resistance mechanism,administration mode,prognosis and application of other drugs in the treatment of MM with targeted drugs in recent years,aiming to provide reference for the treatment and research of MM.
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