Efficacy of Wet-Wrap Therapy in Adults with Moderate to Severe Atopic Dermatitis and Other Dermatitis and Eczema
Objective To observe the efficacy and safety of wet-wrap therapy in adults with moderate to severe atopic dermatitis and other dermatitis and eczema.Methods We retrospectively reviewed clinical records and laboratory results of adult patients with moderate to severe atopic dermatitis and other dermatitis and eczema who were received wet-wrap therapy(WWT)and hospitalized in the Department of Dermatology,Beijing Friendship Hospital affiliated to Capital Medical University from January 2015 to May 2023.The efficacy and adverse reactions were observed before and after treatment.Results A total of 44 patients were collected,and the diagnosis included AD,erythroderma,hypereosinophilic dermatitis,eczema,prurigo nodularis,photosensitive dermatitis and drug eruption.After treatment,the patient's eczema area and severity index(EASI)score,investigator's global assessment(IGA)score,body surface area(BSA)and itch numeric rating scale(NRS)score were significantly improved,and peripheral blood eosinophil cells' level decreased compared with before.The application time of WWT in prurigo nodularis group was significantly longer than that in AD,erythroderma and eczema group,respectively.After treatment,the reduction rate of EASI score in WWT treated with halometasone cream 0.05%group was significantly higher than that in Mometasone Furoate cream 0.1%group and Qingpeng ointment group,respectively.The IGA score in WWT treated with halometasone cream 0.05%group was significantly lower than that in Qingpeng ointment group after treatment.Conclusion WWT is an effective and safe treatment for moderate to severe AD,dermatitis and eczema in adults.
万方数据
维普
