Keratinocyte skin cancer(KSC)is a kind of tumor with increasing incidence rate year by year,which is directly related to annual ultraviolet radiation.KSC stands for different stages of skin cancer including actinic keratosis(AK),Bowen's Disease(BD)and invasive squamous cell carcinoma(SCC).The diagnosis of KSC is mainly confirmed through histopathology.Non-invasive diagnosis is particularly important in the screening and follow-up of KSC.Dermoscopy and reflection confocal microscopy(RCM)are non-invasive diagnostic techniques for observing the surface and sub epidermal structures of the skin in vivo.Dermoscopy and RCM have extremely high application value in the diagnosis of skin diseases.This article mainly summarizes the characteristics of KSC under dermatoscopy and RCM,as well as the application of dermatoscopy and RCM in assisting the diagnosis,screening and follow-up of KSC.
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