The Significance of Clinical Manifestations and Skin Imaging in Diagnosis of Non-Infectious Onychopathy
Objective The main points were analyzed and summarized combined with the medical imaging data and pathological results,which further improving the diagnosis accuracy of noninfectious onychopathy.Methods The study included a total of 48 patients diagnosed with onychopathy who underwent simultaneous nail biopsy and imaging examination from January 2022 to December 2023.The collected images were subsequently analyzed.Results For cases of onychopathy involving a single finger(toe),dermoscopic examination revealed longitudinal cord-like erythema and vascular expansion in onychoglobus,onychopapilloma,psoriasis and onycholichen planus,among which onychopapilloma also showed characteristic subungual keratinized mass.Both subungual exostosis and subungual squamous cell carcinoma exhibited homogeneous proliferative structures;however,the background of subungual squamous cell carcinoma appeared erythematous,with indistinct lesion margins,accompanied by dendritic vessels and evidence of bleeding.Different imaging manifestations can be observed in onychopathy cases of involving multiple fingers(toes),such as psoriasis and lichen planus.Dermoscopy reveals that the ratio of longitudinal nail clefts is significantly higher in cases of nail lichen planus compared to those with nail psoriasis(P<0.05).Furthermore,there is a statistically significant increase in the proportion of punctate depressions and oil droplet structures in psoriasis when compared to lichen planus(P<0.05).Ultrasound in dermatology showed that almost all subungual glomus tumors were subungual low echo nodules with rich blood flow signals.Conclusion Imaging technology such as dermoscopy and ultrasonography has a high reference value for the diagnosis of non-infectious onychopathy.