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恶性单纯性汗腺棘皮瘤1例

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患者女,64岁,右腰部肿物20余年,近5年逐渐增大.皮肤科情况:右腰部单发红褐色增生性斑块,面积约3.5cm ×4.0cm,边缘不规则、表面粗糙,可见红褐色痂皮.皮损组织病理示:角化过度,棘层不规则增生肥厚,肿瘤细胞呈长方形或卵圆形,胞浆呈苍白嗜酸性,核空泡,核仁小,不典型有丝分裂;肿瘤细胞大部分位于表皮内,未见肿瘤浸润.诊断:恶性单纯性汗腺棘皮瘤.治疗:予以局部扩大切除.术后随访15个月未见局部复发及周身淋巴结转移.
Malignant Hidroacanthoma Simplex:A Case Report
A 64-year-old female presented with a right lumbar mass for over 20 years,gradually increasing in size in the last 5 years.Dermatological examination showed a solitary reddish-brown proliferative plaque on the right waist,approximately 3.5 cm ×4.0 cm in size,with irregular edges and a rough surface,covered by reddish-brown crusts.Pathological examination showed hyperkeratosis,irregular hyperplasia and hypertrophy of the stratum spinosum,and tumor cells were rectangular or oval,with pale eosinophilic cytoplasm,vacuolated nuclei,small nucleoli,and atypical mitosis.Most tumor cells were located in the epidermis and no tumor infiltration was seen.This case was diagnosed as malignant hidroacanthoma simplex.Treatment:local extended excision.No local recurrence or peripheral lymph node metastasis was seen in the 15-month postoperative follow-up.

Malignant hidroacanthoma simplexSurgical resection

张萌、任项项、刘领云、杨帆

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河北大学附属医院皮肤科,河北保定 071000

河北大学附属医院普通外科,河北保定 071000

河北大学附属医院病理科,河北 保定 071000

恶性单纯性汗腺棘皮瘤 手术切除

保定市科技局计划项目河北大学附属医院院内基金项目

2241ZF3112022QB29

2024

皮肤科学通报
西安交通大学

皮肤科学通报

CSTPCD
影响因子:0.273
ISSN:1001-8077
年,卷(期):2024.41(4)
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