Progress on Cerebral Glucose Metabolism Patterns of PET Imaging in Parkinson's Disease
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帕金森病是常见的神经退行性疾病,严重影响患者的生存质量,其早期精准诊断是目前医学一大难题.PET 可无创、在体监测帕金森病患者早期脑病理生理改变,具有良好的临床应用价值.18F-FDG PET 脑葡萄糖代谢显像是获取最便利、应用最广泛的检测方法.目前已发现多种帕金森病脑内特异性脑代谢模式,对其早期诊断、鉴别诊断、病情监测及疗效判断均有良好效果.本文重点对帕金森病PET葡萄糖代谢模式进行综述,使其更好地应用于帕金森病的诊断.
Parkinson's disease(PD)is a common neurodegenerative disease,which seriously affects the quality of life of patients.The early and accurate diagnosis of PD is still a major medical problem.Positron computed tomography(PET)can be used to monitor noninvasively the pathophysiological changes in the early stage of PD in vivo,which has good clinical application value.18F-FDG PET cerebral glucose metabolism imaging is the most convenient and widely used detection method.At present,a variety of specific cerebral metabolic patterns of PD have been found,which have good guidance for the early diagnosis,differential diagnosis,disease monitoring and curative efficacy judgment of PD.Therefore,this paper focuses on the review of the 18F-FDG PET cerebral glucose metabolism model related to PD,aiming to enable a better application of this technique to the diagnosis of PD.
NETL
NSTL
万方数据
