首页|多参数磁共振成像评估局部进展期直肠癌新辅助放化疗疗效的研究进展

多参数磁共振成像评估局部进展期直肠癌新辅助放化疗疗效的研究进展

Progress of Multi-Parameter Magnetic Resonance Imaging in Evaluating the Efficacy of Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer

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新辅助放化疗是目前局部进展期直肠癌标准治疗模式的一部分,可以使一定比例的患者达到肿瘤完全缓解,进而提高手术切除率和保肛率,延长患者无病生存期.MRI是评估直肠癌新辅助放化疗疗效的首选影像学检查.随着功能MRI技术的发展,不同成像原理衍生的定量参数可以提供更多的肿瘤生物学信息,提高MRI的临床应用价值.常规MRI序列与功能成像序列相结合的多参数MRI技术可以更加全面地评估新辅助治疗疗效,有助于临床实践中为患者制订个体化的治疗方案,实现精准医疗.
Neoadjuvant chemoradiotherapy is a part of the current standard treatment mode for locally advanced rectal cancer,which enables a certain proportion of patients to achieve complete tumor response,improving the surgical resection rate and anal retention rate,and then prolonging the disease-free survival period of patients.MRI is the preferred imaging examination to evaluate the efficacy of neoadjuvant therapy.With the development of functional MRI,quantitative parameters derived from different imaging principles can provide more biological information about tumors,improving the clinical application value of MRI.Multi-parameter MRI combining conventional MRI sequences and functional sequences can more comprehensively evaluate the efficacy of neoadjuvant therapy,which is conducive to developing individualized treatment plans for patients in clinical practice and realize precision medicine.

Rectal neoplasmsMagnetic resonance imagingDiffusion-weighted imagingChemotherapy,adjuvantTreatment outcomeReview

王笑、刘文广、裴贻刚、李文政

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中南大学湘雅医院放射科,湖南 长沙 410008

直肠肿瘤 磁共振成像 扩散加权成像 化学疗法,辅助 治疗结果 综述

国家自然科学基金

82271984

2024

中国医学影像学杂志
中国医学影像技术研究会

中国医学影像学杂志

CSTPCD北大核心
影响因子:1.37
ISSN:1005-5185
年,卷(期):2024.32(3)
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