自旋锁定频率对心肌定量T1ρ成像的影响
Influence of Spin-Lock Frequency on Quantitative Assessment of Myocardial T1ρ Mapping
韩彩云 1邓炜 1赵韧 2束宏敏 1王震 1杨金秀 1余永强 1李小虎1
作者信息
- 1. 安徽医科大学第一附属医院医学影像科,安徽 合肥 230022
- 2. 安徽医科大学第一附属医院心血管内科,安徽 合肥 230022
- 折叠
摘要
目的 探究在3.0T MR系统下,自旋锁定频率对心肌定量T1ρ值的影响.资料与方法 前瞻性纳入2023年7-9月在安徽医科大学第一附属医院行心脏磁共振检查的38名健康志愿者.使用3.0T MR系统进行T1ρ mapping及短轴电影成像扫描.获得自旋锁定频率为5 Hz、300 Hz、400 Hz、500 Hz的左心室短轴T1ρ图像,分别测得各节段T1ρ值和心肌纤维化指数,采用单因素重复测量方差分析观察不同自旋锁定频率下T1ρ值和心肌纤维化指数的差异.结果 5 Hz、300 Hz、400 Hz、500 Hz的T1ρ值分别为(33.9±2.8)ms、(43.4±2.1)ms、(45.4±2.6)ms、(46.5±2.4)ms,自旋锁定频率越高,T1ρ值越大,且不同自旋锁定频率的T1ρ值之间差异有统计学意义(300 Hz比 400 Hz:P<0.001;300 Hz比 500 Hz:P<0.001;400 Hz比 500 Hz:P=0.043).300 Hz、400 Hz、500 Hz下的心肌纤维化指数分别为(9.4±2.2)ms、(11.3±2.9)ms、(12.6±2.7)ms,差异有统计学意义(300 Hz比400 Hz:P<0.001;300 Hz比500 Hz:P<0.001;400 Hz比500 Hz:P=0.033).结论 本研究提供了特定心脏磁共振设置下健康成人的心肌T1ρ值,结果表明自旋锁定频率可以影响T1ρ值.
Abstract
Purpose To explore the influence of different spin-locking frequencies on T1ρ values based on a 3.0T MR system.Materials and Methods Thirty-eight healthy adult volunteers underwent cardiac magnetic resonance imaging at the First Affiliated Hospital of Anhui Medical University from July to September 2023.T1ρ mapping and short-axis cine imaging with steady-state free precession sequences were performed with 3.0T MR system.T1ρ mapping sequence in three short-axis slices with three spin-lock frequencies at the amplitude of 5 Hz,300 Hz,400 Hz,and 500 Hz was scanned,respectively.T1ρ relaxation times and myocardial fibrosis index were quantified for each slice and each myocardial segment,the difference in T1ρ of different spin-locking frequencies and myocardial fibrosis index was analyzed using one-way repeated-measures analysis of variance method.Results T1ρ of 5 Hz,300 Hz,400 Hz,and 500 Hz were(33.9±2.8)ms,(43.4±2.1)ms,(45.4±2.6)ms and(46.5±2.4)ms,respectively;and T1ρ values showed a significant progressive increase from the low spin-lock frequency to the high spin-lock frequency of the heart(300 Hz vs.400 Hz:P<0.001;300 Hz vs.500 Hz:P<0.001;400 Hz vs.500 Hz:P=0.043).In addition,the measured myocardial fibrosis index at 300 Hz,400 Hz and 500 Hz were(9.4±2.2)ms,(11.3±2.9)ms and(12.6±2.7)ms,respectively.Statistical analysis underscored significant variations among these measurements(300 Hz vs.400 Hz:P<0.001;300 Hz vs.500 Hz:P<0.001;400 Hz vs.500 Hz:P=0.033).Conclusion In this prospective study,myocardial T1ρ values for the specific cardiac magnetic resonance setting are provided,and we found that spin-lock frequency can affect the T1ρ values.
关键词
心肌/心肌纤维化/磁共振成像/T1ρ/mapping/自旋锁定成像Key words
Myocardium/Myocardial fibrosis/Magnetic resonance imaging/T1ρ mapping/Spin-lock frequency引用本文复制引用
基金项目
安徽省临床医学研究转化项目(202304295107020027)
安徽省临床医学研究转化项目(202304295107020028)
安徽省临床医学研究转化项目(202304295107020029)
出版年
2024
NETL
NSTL
万方数据