首页|增强CT灰度共生矩阵预测cN0期甲状腺乳头状癌中央区淋巴结转移

增强CT灰度共生矩阵预测cN0期甲状腺乳头状癌中央区淋巴结转移

Enhanced CT Gray-Level Co-Occurrence Matrix for Predicting Central Lymph Node Metastasis in cN0 Papillary Thyroid Carcinoma

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目的 探讨增强CT灰度共生矩阵预测cN0期甲状腺乳头状癌中央区淋巴结转移的价值.资料与方法 回顾性分析2020年1月—2021年12月徐州市中心医院经临床、手术病理确诊的cN0期甲状腺乳头状癌患者55例,根据术后病理结果分为中央区淋巴结转移阳性组34例、阴性组21例,患者术前均行颈部CT双期增强检查.采用Image J软件分别提取动、静脉期肿瘤最大层面灰度共生矩阵参数(能量、对比、相关、逆差矩、熵)并比较两组各参数的差异,使用受试者工作特征曲线评估参数的预测效能.结果 两组间动脉期能量、熵及静脉期熵差异有统计学意义(t/Z=-2.140、2.753、2.736,P<0.05),其他参数差异均无统计学意义(P>0.05).动脉期能量、动脉期熵、静脉期熵、动脉期能量动脉期熵联合预测中央区淋巴结转移的曲线下面积分别为 0.672、0.706、0.686、0.734,动脉期能量动脉期熵联合预测效能最佳,敏感度和特异度分别为 76.47%、66.67%.结论 增强CT灰度共生矩阵有助于术前预测cN0期甲状腺乳头状癌患者中央区淋巴结转移,动脉期参数能量联合熵的预测效能最佳.
Purpose To investigate the value of enhanced CT gray-level co-occurrence matrix(GLCM)for predicting central lymph node metastasis(CLNM)in cN0 papillary thyroid carcinoma.Materials and Methods Between January 2020 to December 2021,55 cases confirmed cN0 papillary thyroid carcinoma in Xuzhou Central Hospital by clinical and surgical pathology were analyzed retrospectively.According to the postoperative pathological results,all 55 cases were divided into CLNM-positive(34 cases)and CLNM-negative groups(21 cases).All patients underwent dual-phase enhanced CT scan of the neck before operation.Image J software was performed to extract the GLCM parameters(angular second moment,contrast,correlation,inverse difference moment,entropy)of the maximum slice of the tumor in the arterial(A)and venous(V)phases,these parameters between the GLCM parameters of CLNM-positive and negative groups were compared.And the receiver operating characteristic curve was applied to evaluate the prediction efficiency.Results A-angular second moment,A-entropy and V-entropy were significant differences between the two groups(t/Z=-2.140,2.753,2.736,all P<0.05),no significant differences were observed in other parameters between the two groups(P>0.05).The area under curve value of A-angular second moment,A-entropy,V-entropy,combined A-angular second moment and A-entropy to predict CLNM was 0.672,0.706,0.686,0.734,respectively.Combined A-angular second moment and A-entropy had the best predictive efficacy,with the sensitivity and specificity were 76.47%and 66.67%,respectively.Conclusion Enhanced CT GLCM has the efficacy to preoperative CLNM in cN0 papillary thyroid carcinoma patients,combined arterial phase parameter A-angular second moment and A-entropy has the best prediction efficiency.

Thyroid cancer,papillaryCentral lymph nodeGray-level co-occurrence matrixTomography,X-ray computed

王晨、李庆、师毅冰

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徐州市中心医院CT/MR室,江苏 徐州 221009

徐州市中心医院病理科,江苏 徐州 221009

甲状腺癌,乳头状 中央区淋巴结 灰度共生矩阵 体层摄影术,X线计算机

2024

中国医学影像学杂志
中国医学影像技术研究会

中国医学影像学杂志

CSTPCD北大核心
影响因子:1.37
ISSN:1005-5185
年,卷(期):2024.32(8)
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