多模式超声技术对类风湿关节炎尺侧腕伸肌腱病变诊断价值的评估
Assessment on the diagnostic value of multimodal ultrasound technique for the lesion of ECU tendon caused by rheumatoid arthritis
史策 1杨珊灵 1勇言杰 1张妍春 1李梅 1姜淑燕1
作者信息
- 1. 烟台市烟台山医院超声科 烟台 264003
- 折叠
摘要
目的:探讨多模式超声技术对类风湿关节炎(RA)患者尺侧腕伸肌腱(ECU)病变诊断价值.方法:选取2021年12月至2023年1月烟台市烟台山医院风湿科确诊的175例RA患者,将其纳入RA组,将50例非RA但存在手腕部临床症状的患者纳入非RA组,另选取50名健康志愿者纳入健康对照组.所有受试者均行腕部常规超声及剪切波弹性成像(SWE)检查,记录腕关节超声图像特征及ECU能量多普勒(PDUS)血流分布情况,SWE测量ECU得出弹性模量值(EI)、速度模量值(VI).比较组间差异,绘制RA患者受试者工作特征(ROC)曲线,确定曲线下面积及最佳截断值.结果:3组ECU的EI、VI比较,差异有统计学意义(F=61.15、61.28,P＜0.05);RA患者EI、VI最佳截断值分别为319.35 kPa和10.55 m/s;RA患者中年龄与病程因素对EI有统计学意义(r=0.19、0.21,P＜0.05),年龄、病程、腕关节超声评分、尺侧腕伸肌腱能量多普勒(ECUPDUS)分级对VI有统计学意义(r=0.19、0.15、-0.16、-0.17,P＜0.05).结论:SWE可以定量、无创评估RA患者ECU硬度信息,对灰阶超声及PDUS进行补充,多模式超声技术可明确判断RA患者ECU病变相关性.
Abstract
Objective:To investigate the study on the diagnostic value of multimodal ultrasound technique for the lesion of extensor carpi ulnaris(ECU)tendon in patients with rheumatoid arthritis(RA).Methods:A total of 175 RA patients who were confirmed by the department of rheumatology of Yantaishan Hospital of Yantai city from December 2021 to January 2023 were selected,and them were included into the RA group.Other 50 patients without RA but with clinical symptoms of wrist were included into the non-RA group,and 50 healthy volunteers were included into the healthy control group.All subjects underwent routine ultrasound and shear wave elastography(SWE)examination on wrist,and then,the characteristics of ultrasound images of wrists and the blood flow distribution of ECU power Doppler ultrasonography(PDUS)were recorded.SWE was used to measure ECU to obtain elastic modulus index(EI)and velocity modulus index(VI).The differences between three groups were compared,and the receiver operating characteristic(ROC)value of RA patients were drawn,so as to confirm the area under curve(AUC)value and optimize cutoff value.Results:There were significant differences in EI and VI of the ECU tendon among three groups(F=61.15,61.28,P<0.05),respectively.The optimal cut-off values of EI and VI were respectively 319.35 kPa and 10.55 m/s in RA patients.In RA patients,age and disease course had significant influences on EI(r=0.19,0.21,P<0.05),and age,disease course,ultrasound score of wrist joint,and grade of power Doppler ultrasonography PDUS of the ECU tendon(ECUPDUS)had significant influences on VI(r=0.19,0.15,-0.16,-0.17,P<0.05).Conclusion:SWE is able to quantitatively and non-invasively assess the stiffness information of the ECU tendon in RA patients.After the supplement of gray-scale ultrasound and PDUS,multimodal ultrasound technique can clearly judge the correlation of the lesions of ECU tendon of RA patients.
关键词
类风湿关节炎(RA)/尺侧腕伸肌腱(ECU)/超声/弹性成像技术Key words
Rheumatoid arthritis(RA)/Extensor carpi ulnaris(ECU)tendon/Ultrasound/Elastography引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据