超声造影对肾透明细胞癌侵袭性的预测价值
Predictive value of contrast-enhanced ultrasound for the invasiveness of clear cell renal cell carcinoma
冯若璇 1钱林学1
作者信息
- 1. 首都医科大学附属北京友谊医院超声科 北京 100050
- 折叠
摘要
目的:探讨超声造影增强特点与肾透明细胞癌侵袭性的关系.方法:回顾性选取2014年1月至2021年11月首都医科大学附属北京友谊医院经手术病理证实的63例肾透明细胞癌患者,根据病理结果将其分为侵袭组(11例)和非侵袭组(52例),分析其超声造影特征,包括增强时间、消退时间、增强程度、增强方式、假包膜征和灌注缺损.结果:肾透明细胞癌超声造影多表现为快进、慢退、高增强、不均匀增强,但两组间比较差异均无统计学意义(P＞0.05).侵袭组和非侵袭组常规超声特征中,肿块大小有显著差异,最大直径的中位数分别约6.60(3.30,8.80)cm和3.60(2.63,4.88)cm,侵袭组的最大直径更大,差异有统计学意义(Z=-2.346,P＜0.05).侵袭组灌注缺损的比例高于非侵袭组,非侵袭组肿瘤假包膜的比例高于侵袭组,差异均具有统计学意义(x2=9.450、5.839,P＜0.05).结论:肿瘤直径越大、灌注缺损比例越高倾向于侵袭性肾透明细胞癌,超声造影特点有助于术前预测肾透明细胞癌的侵袭性,进而为临床治疗方案提供依据.
Abstract
Objective:To explore the relationship between the characteristics of contrast-enhanced ultrasound and the invasiveness of clear cell renal cell carcinoma.Methods:A total of 63 patients with clear cell renal cell carcinoma who were confirmed by surgical pathology of Beijing Friendship Hospital of Capital Medical University from January 2014 to November 2021 were selected retrospectively.According to the results of pathology,they were divided into an invasive group(11 cases)and a non-invasive group(52 cases).The features of contrast-enhanced ultrasound,which included perfusion time,regression time,enhancement degree,enhancement mode,pseudocapsule and perfusion defect,were analyzed.Results:The contrast-enhanced ultrasound of clear cell renal cell carcinoma mostly showed fast perfusion,slow regression,high enhancement and uneven enhancement,while there were no significant differences between the two groups(P>0.05).In the comparison of the features of routine ultrasound of invasive group and non-invasive group,there was significant difference in the size of tumor,and the medians of the maximum diameters of them were respectively 6.60(3.30,8.80)cm and 3.60(2.63,4.88)cm.The maximum diameter of invasive group was larger,and there was significant difference between the two groups(Z=-2.346,P<0.05).The ratio of perfusion defect of invasive group was significantly higher than that of non-invasive group,and the ratio of pseudocapsule of tumor of non-invasive group was significantly higher than that of invasive group,and there were significant differences between the two groups(x2=9.450,5.839,P<0.05).Conclusion:A larger diameter of the tumor and a higher ratio of perfusion defect prefer to invasive clear cell renal cell carcinoma,and the features of the contrast-enhanced ultrasound will contribute to predict the invasiveness of clear cell renal cell carcinoma before surgery,which may provide the basis for clinical treatment.
关键词
超声造影/肾透明细胞癌/微血管密度/预测Key words
Contrast-enhanced ultrasound/Clear cell renal cell carcinoma/Microvessel density/Prediction引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据