摘要
目的:研究基于5G网络体外膜肺氧合(ECMO)技术在急性呼吸窘迫综合征中的临床应用.方法:选取2020年3月至2022年6月新疆医科大学第一附属医院收治的96例急性呼吸窘迫综合征患者,采取随机数表法将其分为观察组和对照组,每组48例.对照组给予有创呼吸机治疗,观察组给予基于5G网络ECMO技术治疗,对比两组治疗前后动脉血气指标、重症监护病房(ICU)内住院时间、机械通气时间、不良反应发生率以及28 d内病死率.结果:治疗后2、12、24和72 h时,观察组与对照组相比血氧饱和度(SatO2)和动脉血氧分压(PO2)升高,动脉血二氧化碳分压(PCO2)降低,两组比较差异有统计学意义(tSatO2=3.362、6.496、9.432、17.612,tPO2=2.644、4.954、9.330、10.211,tPCO2=5.450、10.927、14.171、17.594,P＜0.05).对照组ICU内平均住院时间为(6.58±2.12)d,观察组为(5.65±1.64)d,两组比较差异有统计学意义(t=2.204,P＜0.05).对照组机械通气平均时间为(4.21±1.55)d,观察组为(3.93±1.20)d,两组比较差异无统计学意义(P＞0.05).对照组28 d内病死率为27.08%(13/48),观察组为8.33%(4/48),两组比较差异有统计学意义(x2=4.376,P＜0.05).结论:基于5G网络ECMO技术在急性呼吸窘迫综合征中的临床应用中可发挥更好的治疗效果,能够更好的纠正患者低氧血症的表现,缩短了ICU平均住院时间,28 d内病死率较低,可获得更好的预后.
Abstract
Objective:To explore and analyze the clinical application of extra corporeal membrane oxygenation(ECMO)technique based on 5th generation(5G)network in acute respiratory distress syndrome(ARDS)complications.Methods:A total of 96 ARDS patients admitted to the First Affiliated Hospital of Xinjiang Medical University from March 2020 to June 2022 were selected,and they were randomly divided into an observation group and a control group,with 48 patients in each group.The control group received the treatment with invasive mechanical ventilation,while the observation group received ECMO treatment based on 5G network.Arterial blood gas indicators,length of stay in intensive care unit(ICU),time of mechanical ventilation,incidence of adverse reactions,and mortality rate within 28 days before and after treatment between the two groups were compared.Results:At the 2nd,12th,24th and 72th hour after treatment,compared with the control group,the observation group showed increased blood oxygen saturation(SatO2)and arterial oxygen partial pressure(PO2),and decreased arterial carbon dioxide partial pressure(PCO2),with statistically significant differences between the two groups(tSato2=3.362,6.496,9.432,17.612,tPO2=2.644,4.954,9.330,10.211,tPCO2=5.450,10.927,14.171,17.594,P<0.05),respectively.The average ICU length of stays of the control group and the observation group were respectively(6.58±2.12)d and(5.65±1.64)d,and the difference of that between two groups was significant(t=2.204,P<0.05).The average times of mechanical ventilation of the control group and the observation group were respectively(4.21±1.55)d and(3.93±1.20)d,and the difference of that between two groups was not significant(P>0.05).The mortality rate within 28 days of the control group and the observation group were 27.08%(13/48)and 8.33%(4/48),and the difference of that between two groups was significant(x2=4.376,P<0.05).Conclusion:The clinical application of ECMO technique based on 5G network in ARDS complications can achieve better therapeutic effects,and can more effectively correct the performance of hypoxemia,and shorten the average ICU length of stay,and reduce the mortality rate within 28 day,which can obtain better prognosis.
基金项目
新疆维吾尔族自治区科技支疆项目(2022E02112)
维普
万方数据