Objective:To investigate the value of Virtual Non-Calcium (VNCa) imaging of single-source dual-energy computed tomography (DECT) in the diagnostic accuracy for bone marrow edema of spinal compression fracture. Methods:The clinical and image data of a total of 60 patients with vertebral compression fracture on thoracic and lumbar vertebrae,who admitted to Wang Jing Hospital of China Academy of Chinese Medical Sciences from January 2021 to June 2022,were retrospectively analyzed. Two doctors conducted subjective assessment for VNCa images under the premise that they did not know results of magnetic resonance imaging (MRI). Then,the diagnostic sensitivity,specificity and accuracy of that for bone marrow edema of fractured vertebral body were calculated. The MR results were used as reference standard to compared whether existed differences in the CT values between edema vertebrae and normal vertebrae. Receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of CT values of VNCa images for spinal bone marrow edema. Results:A total of 451 vertebral bodies were observed in 60 patients,which included 238 thoracic vertebrae and 213 lumbar spine. MRI diagnosis confirmed 83 vertebral bone marrow edema and 368 normal vertebral body. MRI examination was used as reference standard,and the sensitivity,specificity and accuracy of using VNCa images by doctors were respectively 87.95％,98.91％ and 96.90％ in diagnosing bone marrow edema of spinal compression fracture. The average CT value of using VNCa image was (-13.82±24.97) HU in determining bone marrow edema,which was significantly higher than that (-51.67±23.78) HU of normal vertebrae,and the differences were significant (t=12.98,P<0.05). The area under curve (AUC) value of ROC curve that was quantitatively determined was 0.867,and the cut-off value of diagnosing bone marrow edema was set at-26.90 HU,and the sensitivity,specificity and accuracy were respectively 78.30％,84.50％ and 86.7％. Conclusion:The vision and quantitative analysis of VNCa images of single-source DECT can effectively diagnose bone marrow edema of vertebral compression fractures.
维普
万方数据
