Objective:To explore the efficacy of magnetic resonance imaging (MRI) and X-ray computed tomography (CT) examinations based on blood perfusion and metabolic status in the assessment of cerebrovascular disease of the elderly. Methods:A total of 92 elderly patients with suspected cerebrovascular disease admitted to Shandong Electric Power Center Hospital from March 2021 to March 2023 were selected. All patients were examined by using MRI and CT based on blood flow perfusion and metabolic status in order to detect cerebral blood flow (CBF),cerebral blood volume (CBV),time to peak (TTP),mean transit time (MTT),as well as glucose metabolism rate (CMRGluc),cerebral oxygen metabolism rate (CMRO2),and oxygen extraction fraction (OEF). Using a four grid table to analyze the efficacy of two examination methods in diagnosing cerebrovascular disease of elderly. Results:Both the perfusion CT and MRI images of cerebral blood flow on axial direction showed reduction,however,the CT showed a greater reduction in CBF and CBV on the affected side,and a greater increase in TTP and MTT on the affected side,and the differences of these indicators on the affected side between CT and MRI were significant (t=26.485,15.404,1.599,3.341,P<0.05),respectively. Both CT and MRI showed cerebral metabolic rate parameters on the affected side decreased,however,CT showed a greater decrease in CMRGluc,CMRO2 and OEF on the affected side,and the differences were statistically significant (t=3.390,2.710,2.996,P<0.05),respectively. The numbers of cases with true positive of CT and MRI were respectively 88 cases and 80 cases in diagnosing cerebrovascular disease of elderly,and the numbers of cases with true negative of them were respectively 2 cases and 1 case. The numbers of cases with false positive of them were respectively 1 case and 4 cases,and the numbers of cases with false negative were respectively 1 case and 5 cases. There was no significant difference in the diagnostic accuracy between CT examination and MRI examination (P>0.05). Conclusion:MRI has a higher sensitivity in detecting the subtle structure and function of brain,but the visualization of MRI on blood vessels is less clear than that of CT. The cerebrovascular disease of elderly patients still need CT and MRI results to make a more accurate diagnosis.