首页|MRI双参数影像组学模型对临床显著性前列腺癌诊断价值研究

MRI双参数影像组学模型对临床显著性前列腺癌诊断价值研究

Diagnostic value of MRI bi-parameter radiomics model for prostate cancer with clinical significance

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目的:基于磁共振成像(MRI)T2脂肪抑制加权像和弥散加权表观弥散系数图的影像组学特征构建磁共振双参数组学模型,研究双参数影像组学模型对临床显著性前列腺癌的诊断价值.方法:回顾性分析2021年1月至2024年2月天水市第一人民医院临床确诊的93例前列腺癌患者影像和病理资料,运用随机数字分组法7:3原则分为训练集(65例)和测试集(28例),分别对其磁共振T2加权脂肪抑制图像和基于弥散加权成像的表观弥散系数图进行预处理和感兴趣区域(ROI)勾画,提取组学特征1197个,运用机器学习支持向量机方法构建T2加权脂肪抑制像和基于弥散加权成像的表观弥散系数图两者联合的双参数组学模型,就该双参数组学模型诊断临床显著性前列腺癌的效能进行评价.结果:基于MRI双参数影像组学模型的训练集和测试集对临床显著性前列腺癌诊断的受试者工作特征(ROC)曲线下面积(AUC)分别为0.928和0.894,灵敏度和特异度分别为84.2%和95.7%.结论:经训练并测试所构建的双参数影像组学模型对临床显著性前列腺癌具有较高的诊断价值,且相对客观、准确,能对临床诊断和治疗临床显著性前列腺癌提供可靠依据.
Objective:To construct a bi-parameter radiomics model of magnetic resonance based on radiomics features of T2 fat suppression weighted images of magnetic resonance and diffusion-weighted apparent diffusion coefficient mapping,and to study the diagnostic value of the bi-parameter radiomics model for prostate cancer with clinical significance. Method:The imaging and pathological data of 93 patients with prostate cancer,who were confirmed at the First People's Hospital of Tianshui from January 2021 to February 2024,were retrospectively analyzed. They were divided into training set (65 cases) and testing set (28 cases) by using 7:3 principle of random number grouping method. The magnetic resonance T2 weighted fat suppression images and apparent diffusion coefficient mapping based on diffusion weighted imaging were preprocessed,and the regions of interest (ROI) were delineated. 1197 radiomics features were extracted. Machine learning support vector machine method was used to construct a bi-parameter omics model,which combined T2 weighted fat suppression images and apparent diffusion coefficient mapping based on diffusion weighted imaging. And then,the efficiency of this bi-parameter omics model of diagnosing prostate cancer with clinical significance was evaluated. Result:The area under curve (AUC) values of receiver operating characteristic (ROC) curve of training group and testing group based on the MRI bi-parameter model were respectively 0.928 and 0.894 in diagnosing prostate cancer with clinical significance. The sensitivity and specificity of that were respectively 84.2% and 95.7%. Conclusion:The constructed bi-parameter radiomics model through training and testing has higher diagnostic value for prostate cancer with clinical significance,and it is relatively objective and accurate,which can provide reliable basis for clinical diagnosis and treatment of prostate cancer with clinical significance.

Prostate cancerMagnetic resonance imaging (MRI)RadiomicsDiagnostic value

杨彦、尤精武、李蕊、李瑞博

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天水市中医医院放射科 天水 741000

天水市第一人民医院放射科 天水 741000

前列腺癌 磁共振成像(MRI) 影像组学 诊断价值

2024

中国医学装备
中国医学装备协会

中国医学装备

CSTPCD
影响因子:0.882
ISSN:1672-8270
年,卷(期):2024.21(12)