Gastric cancer is one of the most common gastrointestinal tumors,and at present,surgical treatment is the primary treatment. Anastomotic leakage is one of the most serious postoperative complications of gastric malignant tumor,once it occurs,it can severely impact patient prognosis and may even lead to death. At present,the clinical researches of anastomotic leakage focus on "early diagnosis,early treatment" after multi-focus operation,but it is lack in effective prevention measures. Intraoperative anastomotic testing (IOAT) is an intraoperative anastomotic testing method that primarily assesses the integrity and blood perfusion of the intraoperative anastomosis through air leak test (ALT),methylene blue leakage test (MBLT),indocyanine green (ICG) fluorescence image,gastroscopy,and other techniques,which can timely identify and treat anastomotic defects during surgery,and reduce the incidence of postoperatively anastomotic leakage,and decrease postoperative mortality,and enhance postoperative quality of life,and shorten hospital stays,and reduce the economic burden on patients. However,a few clinical studies have shown that IOAT cannot prevent postoperative anastomotic leakage and might lead to necrosis of anastomotic tissue. To review the progress of IOAT technique in radical gastrectomy for gastric cancer,and to summarize the relationship between IOAT and the incidence of postoperative anastomotic leakage,will provide a clinical reference for the prevention of anastomotic leakage after surgery for gastric cancer.
Intraoperative anastomotic testing (IOAT)Gastric cancerAir leak test (ALT)Methylene blue leakage test (MBLT)Indocyanine green (ICG)GastroscopyAnastomotic leakage