柳珊瑚Verrucella sp.中几种化学成分的分离与结构鉴定
Isolation and Structure Identification of Several Chemical Constituents in Gorgonian Verrucella sp.
王玮 1徐石海 1廖小建1
作者信息
摘要
目的 对柳珊瑚Verrucella sp.的化学成分进行分离与结构鉴定.方法 采用反复硅胶柱色谱法及重结晶技术进行分离和纯化,根据理化性质及现代波谱技术确定化合物的结构.结果 从柳珊瑚Verrucella sp.的乙酸乙酯提取物中分离鉴定了7个化合物,其结构分别确定为:junceellin(1),praelolide(2),胆甾醇(cholesterol,3),(E)-N-2(1,3-二羟基4-十八烯基)-十六酰胺[(E)-N-2-(1,3-dihydroxy octadecan-4-en)-hexadecamide,4],胸腺嘧啶(thymine,5),胸腺嘧啶脱氧核苷(thymidine,6),鲨甘醇(batyl alcohol,7).结论 化合物1～7均为首次从该珊瑚中分离得到.
Abstract
OBJECTIVE To isolate and identify the chemical constituents in gorgonian Verrucella sp. METHODS Chromatogra-phy and recrystallization were performed for the isolation and purification, the structures were determined by extensive spectroscopic a-nalysis in association with physical and chemical properties. RESULTS Seven compounds were isolated from the CH_3 COOCH_2 CH_3 extracts of gorgonian Verrucella sp., their structures were identified as junceellin(1), praeiolide (2), cholesterol (3), (E)-N-2-(1,3-dihydroxy octadecan-4-en) -hexadecamide (4), thymine(5), thymidine (6)and batyl alcohol (7). CONCLUSION All the com-pounds were isolated from the gorgonian for the first time.
关键词
柳珊瑚/Verrucella/sp/化学成分Key words
gorgonian/Verrucella sp/chemical constituents引用本文复制引用
基金项目
国家高技术研究发展计划(863计划)(2006AA09Z408)
国家自然科学基金(20772048)
出版年
2010
NETL
NSTL
维普
万方数据