Progress in Application of Flow-through Cell Method for Determination of Drug Dissolution
OBJECTIVE To indroduce the research progress and application of an innovative dissolution test method-flow-through cell method (FTC).METHODS The development process,application of the principle,key problems and utilization examples of FTC were reviewed in this article based on the published papers worldwide.RESULTS AND CONCLUSION As an innovative dissolution test method,flow-through cell method (FTC) has many obvious advantages compared with the conventional paddle/basket method.It overcomes some shortcomings of traditional dissolution methods,especially in the determination of controlled-release formulations and some new preparations.