Chemical Constituents from the Fruits of Embelia laeta
OBJECTIVE To study the chemical constituents of the fruits of Embdia laeta.METHODS The compounds were isolated and purified by MCI,medium pressure TLC on silica gel column,ODS column chromatography,semi-preparative HPLC,and so on.The structures were elucidated on the basis of various modern spectroscopic techniques using physical,chemical properties and spectral data.RESULTS Fifteen compounds were isolated and identified as nantenine(1),oxonantenine(2),physcion(3),syringic acid(4),vanillic acid (5),stigmast-4-ene-3,6-dione (6),(+)-lyoniresinol (7),7S,8S-threo-4,7,9,9'-tetrahydroxy-3,3 '-dimethoxy-8-O-4'-neolignan (8),1,3-dfihydroxylpropyl-(9Z,12Z)-octadeca-9,12-dienate(9),(22E)-5a,8a-epidioxyergosta-6,22-dien-3b-ol(10),dihydroxyisoechinulin A(11),hydroxybenzoic acid(12),stigmasterol(13),sitosterol(14),and daucosterol(15).CONCLUSION Compounds 1,2,and 5-13 are isolated from the genus Embelia for the first time,and compounds 1-15 are isolated from this plant for the first time.