Research Progress on Processing Technology,Chemical Constituents and Pharmacology of Euphorbia pekinensis
Euphorbia pekinensis is a traditional medicine of draining water,dispersing swelling and dissipating binds,first recorded in Shennong's Herbal Classic of Materia Medica.E.pekinensis is used to treat edama,phlegm-fluid retention,carbuncle swollen and toxic and other disease.The major components of E.pekinensisinclude diterpenoids,triterpenoids,flavonoids,coumarins,organic acids and tannins.E.pekinensis has always emphasized the use of processed products as medicine due to strong toxicity.After process-ing,its drug properties and chemical components are changed,under heating and acidic conditions,diterpenoids undergo oxidation,hydrolysis and rearrangement,which lead to structural transformation and decrease in content,while glycoside-containing compounds undergo hydrolysis,resulting in an increase in the content of aglycones.This paper summarizes the processing history,composition changes,pharmacological effects and toxicity comparison of E.pekinensis by consulting literature over the years,which provides refer-ence for the rational development and utilization of medicinal material resources of E.pekinensis.
Euphorbia pekinensisprocessingpharmacological activitytoxicity
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