摘要
目的 研究红凉伞(Ardisia crenata var.bicolor)根中的化学成分.方法 红凉伞根体积分数70％乙醇提取物采用硅胶柱色谱、Sephadex LH-20凝胶柱色谱、ODS反向柱色谱以及制备型高效液相进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构.结果 从中分离得到12个化合物,分别鉴定为异落叶松脂素-3α-O-β-D-吡喃葡萄糖苷(1)、异落叶松脂素-4-O-β-D-吡喃葡萄糖苷(2)、南烛木树脂酚(3)、lyoniside(4)、异落叶松脂素(5)、南烛木树脂酚-3α-O-β-D-吡喃葡萄糖苷(6)、psy-chotrianoside G(7)、pridentigenin E(8)、3β-O-{β-D-吡喃葡萄糖基-(1→2)-α-L-吡喃阿拉伯糖基}-西克拉敏 A(9)、ardisimamil-loside H(10)、3β-O-{ α-L-吡喃鼠李糖基(1→2)-β-D-吡喃葡萄糖基(1→4)-α-L-吡喃阿拉伯糖基}-西克拉敏A(11)、foegraecu-mosideL(12).结论 化合物1～6、12为首次从紫金牛属中分离得到,化合物1～9、12为首次从该植物中分离得到.
Abstract
OBJECTIVE To study the chemical constituents from the roots of Ardisia crenata var.bicolor.METHODS The 70％ethanol extract from A.crenata was isolated and purified by silica,Sephadex LH-20,ODS,and preparative RP-HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Twelve compounds were isolated and identified as isolariciresinol-3α-O-β-D-glucopyranoside(1),isolariciresinol-4-O-β-D-glucopyranoside(2),lyonires-inol(3),lyoniside(4),isolariciresinol(5),lyoniresinol-3α-O-β-D-glucopyranoside(6),psychotrianoside G(7),pridentigenin E(8),3β-O-{β-D-glucopyranosyl-(1→2)-α-L-arabinopyranoside｝-cyclamiretin A(9),ardisimamilloside H(10),3β-O-1 α-L-rham-nopyranosyl-(1 →2)-β-D-glucopyranosyl(1 →4)-α-L-arabinopyranosl｝-3β-hydroxy-13β,28-epoxy-16α-hydroxy-30-al(11),foe-graecumoside L(12).CONCLUSION Compounds 1-6 and 12 are isolated from Ardisia for the first time,and compounds 1-9,12 are isolated from this plant for the first time.
基金项目
国家重点研发计划(2018YFC1708100)
贵州高层次创新人才培养项目(黔科合人才20154032)
贵州省基础科学重点项目(黔科合基础[2019]1402)
贵州省科技计划(黔科合基础-ZK[2023]一般419)
贵州中医药大学科研创新和探索专项(2018YFC170810102)
贵州中医药大学科研创新和探索专项(2018YFC170810208)
维普
万方数据