中国药学杂志2024,Vol.59Issue(8) :664-675.DOI:10.11669/cpj.2024.08.002

洋甘菊的化学成分和药理作用研究进展及其质量标志物预测分析

Research Progress on Chemical Constituents and Pharmacological Effects of Matricaria chamomilia L.and Predictive Analysis of Quality Markers

李晶晶 陈少影 兰卫
中国药学杂志2024,Vol.59Issue(8) :664-675.DOI:10.11669/cpj.2024.08.002

洋甘菊的化学成分和药理作用研究进展及其质量标志物预测分析

Research Progress on Chemical Constituents and Pharmacological Effects of Matricaria chamomilia L.and Predictive Analysis of Quality Markers

李晶晶 1陈少影 1兰卫1
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作者信息

  • 1. 新疆医科大学中医学院,乌鲁木齐 830017
  • 折叠

摘要

洋甘菊(Matricaria chamomilla L.)为菊科母菊属草本植物,是维吾尔医学常用药材,主产于中国新疆和欧洲等地.洋甘菊的化学成分主要包括黄酮、酚酸、挥发油、香豆素和其他类成分,具有抗炎、镇痛、抗菌、抗氧化、抗肿瘤、降血糖、降血脂、降血压和对胃肠道系统和神经系统的药理作用.本文在对洋甘菊化学成分、药理作用概述的基础上,对其质量标志物进行预测分析,推测黄酮、酚酸、倍半萜类成分可作为洋甘菊的质量标志物,为建立洋甘菊质量标准提供科学参考.

Abstract

Matricaria chamomilla L.is a herbaceous plant belonging to Asteraceae family.It is frequently used as medicinal herb in the Uygur medicines and is mainly produced in Xinjiang Uygur autonomous region,Europe and other places.Its chemical constitu-ents mainly include flavonoids,phenolic acids,essential oil,coumarins and other compounds.This herb has anti-inflammatory,anal-gesic,antibacterial,antioxidant,anti-tumor,hypoglycemic,hypolipidemic,hypotensive and pharmacological effects on gastrointestinal and nervous system.Based on the overview of the chemical constituents and pharmacological effects of chamomile,this paper conducts a predictive analysis of its quality markers.It is speculated that flavonoids,phenolic acids and sesquiterpenoids can be used as quality markers of chamomile,providing scientific reference for establishing its quality standards.

关键词

洋甘菊/黄酮/药理作用/质量标志物

Key words

Matricaria chamomilla L./flavonoid/pharmacological activity/quality marker

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基金项目

国家自然科学基金地区科学基金(81960771)

新疆药学会科研基金(YXH202106)

出版年

2024
中国药学杂志
中国药学会

中国药学杂志

CSTPCD北大核心
影响因子:0.957
ISSN:1001-2494
参考文献量115
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