Advance in Role of Circular RNA on Neurovascular Units and its Application
Circular RNAs(circRNAs)are a class of single-stranded RNA molecules with covalently closed continuous loops which are involved in the occurrence and development of diseases.Neurovascular units(NVU)refer to the cellular and molecular interfaces between the circulatory system and central nervous system(CNS),mainly composed of microvascular cells,glial cells,neurons,and extracellular matrix,which are of great significance for maintaining brain homeostasis.However,the role of circRNA on NVU remains unknown.This article summarizes the latest research progress,with the aim of providing new targets and strategies for the treatment of related diseases.
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