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功能性水凝胶在伤口愈合中的研究进展

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纱布、棉花和绷带等传统敷料,存在透性差、更换时容易造成二次伤害等缺点,在医疗实践中已逐步减少使用。与传统敷料相比,功能性水凝胶因其具有优异的生物相容性、高保水性、易引入功能成分的优点和加速伤口愈合等特性而备受关注。本文介绍了皮肤伤口愈合的机制和不同类型的伤口敷料的性能,总结了近五年以来,通过物理或者化学交联方式构建的功能性水凝胶的研究进展,对功能性水凝胶的未来发展趋势作出了展望。
Research Progress in Functional Hydrogels in Wound Healing
The use of traditional dressings,such as gauze,cotton and bandages,has been gradually reduced in medical practice due to their disadvantages,including poor permeability and the tendency to cause secondary injuries during replacement.In contrast,functional hydrogels have attracted much attention due to their excellent biocompatibility,high water retention,ease of introduction of functional components and accelerated wound healing.This paper describes the mechanisms of skin wound healing and the properties of different types of wound dressings.It summarizes the research progress in functional hydrogels constructed by physical or chemical crosslinking over the past five years.Additionally,it offers insights into the future development trends of functional hydrogels.

wound dressingfunctional hydrogelphysical crosslinkingchemical crosslinkingnatural polymersynthetic polymer

陈美怡、王琼、祝传营、张牧霖、刘想、詹海莺

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广东药科大学医药化工学院,广东中山 528458

广东省化妆品工程技术研究中心,广东中山 528458

伤口敷料 功能性水凝胶 物理交联 化学交联 天然聚合物 合成聚合物

2024

中国药学杂志
中国药学会

中国药学杂志

CSTPCD北大核心
影响因子:0.957
ISSN:1001-2494
年,卷(期):2024.59(21)