Dydrogesterone Combined with Hysteroscopic for Treating Early Endometrial Carcinoma and Its Influence on Reproductive Function in 30 Cases
Objective To observe the effect of dydrogesterone combined with hysteroscopic in treating early endometrial carcinoma, and its influence on reproductive function. Methods 60 cases of early endometrial carcinoma patients from February 2010 to February 2010 were randomly divided into the observation group and the control group, 30 cases in each group. The control group received megestrol acetate therapy, the observation group received dydrogesterone combined with hysteroscopic. The clinical efficacies of the two groups were compared, and the intraoperative complications were recorded;the serum CA125 ( carbohydrate antigen 125 ) level, the recurrence rate and pregnancy postoperative 2-4 years were recorded; the adverse reactions were observed during treatment. Results The total remission rate of the observation group was 83. 33%, which was higher than 70. 00% of the control group ( P ﹤ 0. 05 );the serum CA125 level of the observation group was significantly lower than that of control group;the recurrence rate of the observation group was 13. 33%, which was significantly lower than 3. 33% of control group ( P ﹤ 0. 05 );and two, the difference was statistically significant ( P ﹤ 0. 05 ) . Compared with the control group, the successful pregnancy rate and term rate of the observation group were significantly increased, and the abortion rate and preterm birth rate of the observation group were significantly lower ( P ﹤ 0. 05 );the adverse reactions such as nausea, weight gain and skin rashes and others had no statistically significant difference between the two group ( P ﹥ 0. 05 ) . Conclusion Dydroges-terone combined with hysteroscopic in treating early endometrial carcinoma can improve the efficacy with lower recurrence rate, can maximum limit to protect the patient's fertility, the prognosis is good, and is worth of clinical promotion.
progesteronehysteroscopicearly endometrial carcinomaclinical curative effectreproductive function
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维普
