Analysis of Potentially Inappropriate Medication in Elderly Patients with Diabetes Mellitus Type 2 in a Hospital
Objective To promote the clinical rational drug use in elderly patients with diabetes mellitus type 2(T2DM).Methods The general data and medication orders of elderly patients with T2DM discharged from the endocrinology department from July 1,2021 to March 31,2022 were extracted by the hospital's electronic medical-record system.Based on the Criteria of Potentially Inappropriate Medications for Older Adults in China(2017 Edition,hereinafter referred to as the Chinese Criteria)and the American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults(hereinafter referred to as the Beers Criteria),the potentially inappropriate medication(PIM)in medication orders of elderly patients after discharge was evaluated,and the possible adverse drug reactions(ADRs)were tracked and evaluated.Results A total of 204 patients were included,including 97 males and 107 females,with an average age of(73.59±6.23)years,involving(7.06±2.69)varieties of medication on average after discharge.A total of 31 medical records(15.20%)involved 37 cases of PIM based on the Chinese Criteria,while 62 medical records(30.39%)involved 77 cases of PIM based on the Beers Criteria.Both evaluation criteria showed that no less than eight varieties of medication after discharge was a risk factor for PIM in elderly patients with T2DM(P<0.05).After removing duplicates of evaluation results base on the two different criteria,there were 76 patients with PIM,of whom four had ADR(5.26%),involving medications such as rivaroxaban,clopidogrel,warfarin + aspirin and furosemide + spironolactone.Conclusion Elderly patients with T2DM may take many varieties of medication after discharge,which may lead to PIM.ADR monitoring outside the hospital is easy to be ignored.The combination of Chinese Criteria and the Beers Criteria can be used for PIM evaluation of elderly patients with T2DM taking medications after discharge to decrease the incidence of PIM and ADR.
diabetes mellitus type 2potentially inappropriate medicationelderly patienttaking medication after dischargeadverse drug reactionrational drug use
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