Medication Analysis for Delayed Henoch-Schonlein Purpura Induced by Naoxintong Capsules:A Case Report
Objective To promote the rational application of Naoxintong Capsules in clinical practice.Methods The treatment process of a patient with delayed Henoch-Schonlein purpura induced by Naoxintong Capsules in the Shandong Provincial Qianfoshan Hospital was retrospectively analyzed.Based on the VigiAccess and literature,the correlation of Naoxintong Capsules with adverse drug reactions(ADRs)was evaluated by the Naranjo's ADR evaluation scale,and the clinical characteristics of this ADR were explored.Results After use of Naoxintong Capsules,the patient experienced paroxysmal abdominal pain complicated with gastrointestinal bleeding.After symptomatic treatment with Methylprednisolone Tablets,Bacillus Licheniformis Capsule,Live and Compound Glutamine Entersoluble Capsules,the patient's rash significantly improved,and she did not experienced any abdominal pain or diarrhea.The patient's severe Henoch-Schonlein purpura was likely related to Naoxintong Capsules(the score of Naranjo's ADR evaluation scale was six points).Conclusion Naoxintong Capsules can induce Henoch-Schonlein purpura,but this ADR is not recorded or warned in the drug instructions.Clinical pharmacists and physicians should strengthen pharmaceutical care,pharmaceutical manufacturers and medical staff should strengthen pharmacovigilance,and relevant departments should revise drug instructions if necessary.
Naoxintong CapsulesHenoch-Schonlein purpuradelayedadverse drug reactionpharmaceutical care
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