Practice of PCNE Classification System in Medication Therapy Management for Patients with Cerebral Infarction
Objective To investigate the role of clinical pharmacists in identifying drug-related problems(DRPs)in patients with cerebral infarction based on the Pharmaceutical Care Network Europe(PCNE)classification system in medication therapy management(MTM),and its effect on patients'clinical outcomes.Methods A total of 80 inpatients with cerebral infarction admitted to the hospital from June to September 2022 were selected and randomly divided into the control group and the intervention group by the random number table method,with 40 cases in each group.The patients in the control group were given traditional treatment mode,while the patients in the intervention group were given pharmaceutical care on the basis of the control group.The PCNE classification system was used to identify DRPs,analyzed the types of problems and causes of DRPs,provide intervention plans,and understand the acceptance of intervention plans by physicians and patients and the resolution status of DRPs.Results A total of 45 DRPs were found in the intervention group,with 21 efficacy problems(46.67%),14 safety problems(31.11%)and 10 other problems(22.22%).There were 47 reasons for DRPs,among which 26 cases were related to medication selection(55.32%),12 cases were related to dose selection(25.53%),7 cases were related to patients(14.89%),and 2 cases were related to treatment course(4.26%).A total of 35 cases(77.78%)were fully accepted by the physician and patient intervention plan,and all 37 cases of DRPs(82.22%)were resolved.Compared with those before treatment,the scores of traditional Chinese medicine syndrome at discharge and one month after discharge in the intervention group were significantly lower(P<0.05),and were significantly lower than those in the control group(P<0.05).The score of 8-item Morisky Medication Adherence Scale(MASS-8)at discharge in the intervention group was significantly higher(P<0.05),and was significantly higher than that in the control group(P<0.05).Both groups showed a significant decrease in the score of the National Institutes of Health Stroke Scale(NIHSS)at discharge and one month after discharge(P<0.05).Conclusion Clinical pharmacists implementing pharmaceutical care based on MTM and PCNE classification system for patients with cerebral infarction can identify and resolve DRPs,improve the traditional Chinese medicine syndrome and the patient's severity condition,enhance the patient's medication compliance,and the physician's acceptance is high.
medication therapy managementPharmaceutical Care Network Europedrug-related problemspharmaceutical carecerebral infarctionclinical pharmacists
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