Prescription Dose of Traditional Chinese Medicine Decoction Pieces in 15 Secondary and Above Medical Institutions in Ningxia
Objective To promote the rational use of traditional Chinese medicine(TCM)decoction pieces in medical institutions in Ningxia.Methods A total of 3 032 TCM prescriptions in the outpatient service of 15 secondary and above medical institutions in different regions of Ningxia Hui Autonomous Region in 2019 were selected from the hospital information system based on the random simple sampling method.The above prescriptions were all prescribed by the physicians with middle or high professional titles who were qualified to prescribe TCM prescriptions in various medical institutions.The use frequency,dose of various TCM decoction pieces and their accordance rate with the regulations of the Chinese Pharmacopoeia(2020 Edition,Volume Ⅰ,referred to as the Pharmacopoeia)were analyzed.Results A total of 615 TCMs were involved,with an average of 15-19 TCMs per dose.The clinical commonly use doses of TCM decoction pieces without the homology of medicine and food were mainly in the range of 4-10 g,11-15 g,16-20 g,while those of TCM decoction pieces with the homology of medicine and food were mainly in the range of 0-10 g,11-20 g,21-30 g.The top three commonly used TCM decoction pieces without the homology of medicine and food were Chuanxiong Rhizoma(765 times,25.23%),Bupleurum chinense(734 times,24.21%),stir-baked Atractylodis Macrocephalae Rhizoma in bran(723 times,23.85%)respectively,and the top three TCM decoction pieces with the homology of medicine and food were Poria(1 275 times,42.05%),Angelicae Sinensis Radix(972 times,32.06%),Liquorice Tablets(923 times,30.44%)respectively.The accordance rates of the clinical commonly use doses of the top 30 commonly used TCM decoction pieces without and with the homology of medicine and food with the regulations of the Pharmacopoeia were 60.03%and 70.35%respectively.The accordance rates of use doses of toxic and low-toxic TCM decoction pieces in 15 medical institutions with the regulations of the Pharmacopoeia were 44.61%and 45.60%respectively.Conclusion The prescription application of TCM decoction pieces in secondary and above medical institutions in Ningxia is generally standardized.In order to ensure the authority,scientificity of the Pharmacopoeia,better conform to clinical practice and ensure medication safety,it is recommended to increase researches on the clinical use dose and efficacy of TCM decoction pieces,revise the dose range of some drugs,distinguish TCM decoction pieces with and without the homology of medicine and food when the Pharmacopoeia is reissued.
TCM decoction piecesChinese Pharmacopoeiaoverdosehomology of medicine and foodnon-homology of medicine and fooddose-effect relationship