Objective To verify the effect of Mehran score applied in the risk assessment of contrast-induced nephropathy(CIN)in elderly patients with coronary heart disease(CHD).Methods The clinical data(including basic information,complications,laboratory indicators,combined medication)of elderly patients(＞65 years)underwent percutaneous coronary intervention(PCI)in the Department of Cardiovascular Medicine of a hospital in Shanghai from January 2015 to December 2017 were collected.The univariate analysis and binary Logistic regression analysis were used to evaluate the risk factors for CIN and its correlation with Mehran score.Results A total of 378 patients were included,of which 45(11.90%)had CIN during the perioperative period;182,147,41,eight patients had low risk(≤five points),medium risk(six to ten points),high risk(11 to 15 points),extremely high risk(≥16 points)respectively based on the Mehran grading,and the incidence of CIN in each group was significantly different(P＜0.05).The binary Logistic regression analysis showed that the preoperative estimated glomerular filtration rate(eGFR)[OR = 0.939,95%CI(0.883,0.998),P = 0.044],high risk of Mehran grading[OR = 3.414,95%CI(1.116,10.441),P = 0.031]and extremely high risk of Mehran grading[OR = 9.604,95%CI(1.311,70.355),P = 0.026]were important factors in predicting the occurrence of CIN in elderly patients with CHD after PCI.Conclusion Preoperative eGFR,high risk,extremely high risk of Mehran grading are the influencing factors in predicting the occurrence of CIN in elderly patients with CHD after PCI.
维普
万方数据