Effect of Esketamine Combined with Conventional Sedatives in Adenoidectomy in Children
Objective To investigate the effect of esketamine combined with conventional sedatives on hemodynamic indicators,postoperative restless behavior,and pain level in children undergoing adenoidectomy.Methods A total of 120 children who underwent adenoidectomy in the Tangshan Maternal and Child Health Hospital from January 2020 to December 2022 were selected and randomly divided into the control group and the study group,with 60 cases in each group.The children in the two groups were anesthetized with conventional sedatives,on this basis,the children in the study group were anesthetized with esketamine.Results Compared with those before anesthesia(T1),the diastolic blood pressure(DBP),systolic blood pressure(SBP),and heart rate(HR)in the two groups at the onset of anesthesia(T2)significantly reduced(P<0.05).Compared with those at T2,the DBP,SBP,and HR in the two groups after 10 min(T3)of anesthesia cessation significantly increased(P<0.05),and the change in the study group was significantly less than that in the control group(P<0.05).Compared with those in the control group,the disappearance time of eyelash reflex,disappearance time of pain response,and recovery room stay time in the study group significantly shortened(P<0.05),and the visual analogue scale(VAS)scores in the study group significantly reduced at 6,12,and 24 h after surgery(P<0.05).The Mini-Mental State Scale(MMSE)score in the study group significantly increased after anesthesia recovery and 3 d after surgery(P<0.05).The incidence of postoperative restlessness in the study group was 11.67%,which was significantly lower than 28.33%in the control group(P<0.05).The incidence of adverse reactions in the study group was comparable to that in the control group(11.67%vs.8.33%,P>0.05).Conclusion Esketamine combined with conventional sedatives has a good anesthesia induction effect on children undergoing adenoidectomy,which can maintain intraoperative hemodynamic stability,improve postoperative cognitive function,reduce postoperative restless behavior,alleviate pain,and it has good safety.
万方数据
维普
