Clinical Observation of Rosuvastatin Combined with Rehabilitation Training in the Treatment of Coronary Heart Disease Complicated with Hyperlipidemia
Objective To investigate the clinical efficacy of rosuvastatin combined with rehabilitation training in the treatment of patients with coronary heart disease(CHD)complicated with hyperlipidemia.Methods A total of 144 patients with CHD complicated with hyperlipidemia admitted to the hospital from January 2020 to December 2022 were selected and divided into the control group and the observation group according to the random number table method,with 72 cases in each group.The patients in the control group received routine treatment and rosuvastatin,on this basis,the patients in the observation group received rehabilitation training.Both groups were treated for 12 weeks.Results After treatment,the levels of total cholesterol(TC),triglycerides(TG),and low-density lipoprotein cholesterol(LDL-C)in the two groups were significantly lower than those before treatment,while level of high-density lipoprotein cholesterol(HDL-C)in the two groups was significantly higher than that before treatment(P<0.05),and those in the observation group were significantly better than those in the control group(P<0.05).The levels of left ventricular ejection fraction(LVEF)and cardiac output(CO)in the two groups were significantly higher than those before treatment,while the level of serum cardiac troponin I(cTnI)in the two groups was significantly lower than that before treatment(P<0.05),and those in the observation group were significantly better than those in the control group(P<0.05).The MOS item short form health survey(SF-36)scores(including physiological function,physiological function,vitality,social function,and overall healthh score)in the two groups was significantly higher than that before treatment(P<0.05),and that in the observation group was significantly higher than that in the control group(P<0.05).Conclusion Rosuvastatin combined with rehabilitation training in the treatment of patients with CHD complicated with hyperlipidemia can effectively improve heart function,adjust blood lipid levels,and quality of life.
rosuvastatinrehabilitation trainingcoronary heart diseasehyperlipidemiaquality of lifeclinical efficacy