Research Progress on the Application of Metabolomics Techniques in Osteoporosis
Objective To summarize the application of metabolomics techniques in osteoporosis.Methods Relevant studies on the application of metabolomics techniques in the pathogenesis,diagnosis,and prevention of osteoporosis in databases such as WanFang and PubMed from the inception of databases to May 2023 were searched.Results Osteoporosis is mainly disordered by amino acid metabolism,lipid metabolism,and energy metabolism,among which differential metabolites can be used as biomarkers for disease prediction,diagnosis and treatment.The combined application of metabolomics and multi-omics is a research hotspot in recent years.Conclusion Metabolomics has great clinical translation potential,from disease prediction to treatment,which provids a new direction for comprehensive research on osteoporosis.
osteoporosisbone mineral densitymetabolomicsdifferential metabolites