首页|麦芪苈汤联合穴位贴敷佐治老年慢性肺源性心脏病并右心衰竭临床研究

麦芪苈汤联合穴位贴敷佐治老年慢性肺源性心脏病并右心衰竭临床研究

扫码查看
目的 探讨麦芪苈汤联合穴位贴敷佐治老年慢性肺源性心脏病(简称肺心病)并右心衰竭的临床疗效。方法 选取医院 2021 年1 月至 2022 年 7 月收治的老年慢性肺心病并右心衰竭患者 102 例,按随机数字表法分为对照组和观察组,各 51 例。两组患者均予常规西医治疗+穴位贴敷,观察组患者加服麦芪苈汤。两组均以 1 周为 1 个疗程,治疗 2 个疗程。结果 观察组患者的总有效率为 94。12%,显著高于对照组的 76。47%(P<0。05)。治疗后,两组患者的中医证候(咳嗽咳痰、胸闷气短、心悸乏力、口唇发绀)积分,血清炎性指标(肿瘤坏死因子-α、白细胞介素 1β、白细胞介素 6)水平及心肌损伤指标(氨基末端脑钠肽前体、心肌肌钙蛋白T、肌酸激酶同工酶MB)水平均显著降低,且观察组患者上述中医证候积分及心肌损伤指标水平均显著更低(P<0。05)。观察组与对照组不良反应发生率相当(7。84%比 9。80%,P>0。05)。结论 麦芪苈汤联合穴位贴敷佐治老年慢性肺心病并右心衰竭,可有效改善患者的中医证候,缓解心肌损伤。
Clinical Study of Maiqili Decoction Combined with Acupoint Application in the Adjuvant Treatment of Elderly Chronic Pulmonary Heart Disease Complicated with Right Heart Failure
Objective To investigate the clinical efficacy of Maiqili Decoction combined with acupoint application in the adjuvant treatment of elderly chronic pulmonary heart disease complicated with right heart failure.Methods A total of 102 elderly patients with chronic pulmonary heart disease and right heart failure admitted to the hospital from January 2021 to July 2022 were selected and divided into the control group and the observation group by the random number table method,with 51 cases in each group.The patients in the two groups were given routine western medicine and acupoint application,on this basis,the patients in the observation group were given Maiqili Decoction.Both groups were treated for two courses with one week as a course.Results The total effective rate in the observation group was 94.12%,which was significantly higher than 76.47%in the control group(P<0.05).After treatment,the scores of traditional Chinese medicine(TCM)syndromes(cough,phlegm,chest tightness,shortness of breath,palpitations,fatigue,cyanosis of the lips),serum inflammatory indexes[tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β),interleukin-6(IL-6)]levels and myocardial injury indexes[amino-terminal pro-B-type natriuretic peptide(NT-proBNP),cardiac troponin T(cTnT)and creatine kinase-MB(CK-MB)]levels were significantly lower,the above TCM syndrome scores and myocardial injury indexes in the observation group were significantly lower(P<0.05).The incidence of adverse reactions in the observation group was similar to that in the control group(7.84%vs.9.80%,P>0.05).Conclusion Maiqili Decoction combined with acupoint application can effectively improve the TCM syndrome of elderly patients with chronic pulmonary heart disease and right heart failure,and relieve their myocardial injury.

Maiqili Decoctionacupoint applicationelderly patientchronic pulmonary heart diseaseright heart failuremyocardial injuryclinical efficacy

王敏妨、刘莉莉、马跃飞、梁东飞、李艳孔、袁胜利、辛元元

展开 >

河北省张家口市中医院,河北 张家口 075000

麦芪苈汤 穴位贴敷 老年患者 慢性肺源性心脏病 右心衰竭 心肌损伤 临床疗效

河北省中医药局中医药类科学研究课题河北省张家口市重点研发计划

20231912121096D

2024

中国药业
重庆市食品药品监督管理局

中国药业

CSTPCD
影响因子:1.369
ISSN:1006-4931
年,卷(期):2024.33(8)
  • 17