Visualized Analysis of Research Hotspots and Trends of Berberine Based on CiteSpace Knowledge Graph
Objective To investigate the research hotspots and trends of berberine based on CiteSpace,and to provide a reference for the clinical application of berberine.Methods The literature related to berberine in the CNKI was searched from January 1,2012 to November 4,2022.CiteSpace 5.7.R5 software was used to visually analyze literature that met inclusion criteria.Results A total of 710 studies were included,and the overall number of publications showed a fluctuating growth trend.A total of 1 065 authors were included,and the core authors were Li Meijuan,Li Ping,Li Min,etc.A total of 779 research institutions were included,and the research institutions with more cooperation were the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine and the Guangdong Provincial Hospital of Traditional Chinese Medicine.The research hotspots included chronic diarrhea,type 2 diabetes mellitus,liver cancer,Alzheimer's disease,etc.The research methods involved experimental research,clinical efficacy observation,etc.Conclusion The research on berberine in China is generally good,and cooperation among authors and research institutions needs to be strengthened.The mechanism of hypoglycemic,anti-tumor,and anti-inflammatory effects of berberine is a future research hotspot and trend.
万方数据
维普
