Objective To screen the pesticide residues in Xiao'er Magan Granules,and to evaluate the safety risks of pesticide residues in Xiao'er Magan Granules.Methods Based on the high-performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)method and gas chromatography-tandem mass spectrometry(GC-MS/MS)method,the residues of 33 prohibited pesticides and 17 restricted pesticides in the preparation of Xiao'er Magan Granules and its raw herbal materials were determined by the pre-treatment method of acetonitrile homogenization extraction/dispersion solid-phase extraction(dSPE)/HLB column purification.Results No prohibited pesticide residue was detected from Xiao'er Magan Granules.Residual pesticide imidacloprid was detected in eight batches of samples from four manufacturers,with the content of 0.002-0.019 mg/kg,which was far below the safety limit of 60 mg/kg.Conclusion The safety of Xiao'er Magan Granules is good,but the residual risk of the pesticide imidacloprid needs to be controlled.
维普
万方数据
