Effect of Modified Qutan Huayu Recipe Combined with Western Medicine on Blood Lipid and Vascular Endothelial Function in Patients with Coronary Heart Disease of Phlegm Turbidity and Blood Stasis Type
Objective To investigate the effect of modified Qutan Huayu Recipe combined with Western medicine on blood lipid and vascular endothelial function in patients with coronary heart disease of phlegm turbidity and blood stasis type.Methods A total of 98 patients with coronary heart disease of phlegm turbidity and blood stasis type admitted to the Beidaihe Rehabilitation and Recuperation Center of the PLA Joint Logistic Support Force from February 2019 to December 2022 were selected and randomly divided into the control group and the observation group,with 49 cases in each group.The patients in the two groups were treated with symptomatic Western medicine,on this basis,the patients in the observation group were treated with modified Qutan Huayu Recipe.Both groups were treated for 28 d.Results No severe adverse reactions occurred in the two groups.The total effective rate in the observation group was 91.84%,which was significantly higher than 69.39%in the control group(P<0.05).After treatment,the levels of serum low-density lipoprotein cholesterol(LDL-C),triglycerides(TG),and total cholesterol(TC)in the two groups were significantly lower than those before treatment(P<0.05),while the level of high-density lipoprotein cholesterol(HDL-C)in the two groups was significantly higher than that before treatment(P<0.05),and those in the observation group were significantly better than those in the control group(P<0.05);the flow-mediated vasodilation(FMD)of the brachial artery and the nitric oxide(NO)level in the two groups were significantly higher than those before treatment(P<0.05),while the level of endothelin(ET)in the two groups was significantly lower than that before treatment(P<0.05),and those in the observation group were significantly better than those in the control group(P<0.05);the Seattle angina questionaire(SAQ)score in the two groups was significantly higher than that before treatment(P<0.05),and that in the observation group was significantly higher than that in the control group(P<0.05).Conclusion Modified Qutan Huayu Recipe combined with Western medicine has good clinical efficacy in the treatment of coronary heart disease of phlegm turbidity and blood stasis type,which can improve vascular endothelial function,regulate blood lipid metabolism,and improve quality of life.
Qutan Huayu Recipecoronary heart diseasephlegm turbidity and blood stasis typeblood lipidvascular endothelial function
万方数据
维普
