Research Progress on Tongxieyaofang Formula in the Treatment of Gastrointestinal Diseases
Objective To provide a reference for the clinical application of Tongxieyaofang Formula in the treatment of gastrointestinal diseases.Methods By searching the literature related to Tongxieyaofang Formula in the treatment of gastrointestinal diseases from January 1992 to December 2023 in CNKI and PubMed databases,the modern pharmacological effects,clinical applications,and mechanisms of Tongxieyaofang Formula in the treatment of gastrointestinal diseases were analyzed.Results Tongxieyaofang Formula has the effect of tonifying the spleen and softening the liver,dispelling dampness,and stopping diarrhea,it is the first choice formula for the treatment of painful diarrhea,and it is widely used in the treatment of gastrointestinal diseases such as ulcerative colitis,chronic colitis,irritable bowel syndrome and other gastrointestinal diseases,with good efficacy and safety.It improves the symptoms of diarrhea by protecting the gastrointestinal mucosa,regulating gut microbiota,anti-inflammatory,improving gastrointestinal motility,alleviating anxiety and depression,and other means.Conclusion Tongxieyaofang Formula is effective and safe in the treatment of ulcerative colitis and other gastrointestinal diseases,but its active ingredients and mechanism need to be further researched.